Publications

Breaking the Silence: Regulation of HIV Transcription and Latency on the Road to a Cure

Natasha N Duggan NN, Dragic T, Chanda SK, Pache L

Viruses. 2023 Dec 15;15(12):2435.

Antiretroviral therapy reveals triphasic decay of intact SIV genomes and persistence of ancestral variants

Fray EJ, Wu F, Simonetti FR, Zitzmann C, Sambaturu N, Molina-Paris C, Bender AM, Liu PT, Ventura JD, Wiseman RW, O'Connor DH, Geleziunas R, Leitner T, Ribeiro RM, Perelson AS, Barouch DH, Siliciano JD, Siliciano RF.

Cell Host Microbe. 2023 Mar 8;31(3):356-372.e5

Repurposing BCL-2 and Jak 1/2 inhibitors: Cure and treatment of HIV-1 and other viral infections

Reece MD, Song C, Hancock SC, Pereira Ribeiro S, Kulpa DA, Gavegnano C.

Front Immunol. 2022 Dec 9;13:1033672

Early intervention with 3BNC117 and romidepsin at antiretroviral treatment initiation in people with HIV-1: a phase 1b/2a, randomized trial

Gunst JD, Pahus MH, Rosás-Umbert M, Lu IN, Benfield T, Nielsen H, Johansen IS, Mohey R, Østergaard L, Klastrup V, Khan M, Schleimann MH, Olesen R, Støvring H, Denton PW, Kinloch NN, Copertino DC, Ward AR, Alberto WDC, Nielsen SD, Puertas MC, Ramos V, Reeves JD, Petropoulos CJ, Martinez-Picado J, Brumme ZL, Jones RB, Fox J, Tolstrup M, Nussenzweig MC, Caskey M, Fidler S, Søgaard OS.

Nat Med. 2022 Nov;28(11):2424-2435

IRF7 expression correlates with HIV latency reversal upon specific blockade of immune activation

Ezeonwumelu IJ, García-Vidal E, Felip E, Puertas MC, Oriol-Tordera B, Gutiérrez-Chamorro L, Gohr A, Ruiz-Riol M, Massanella M, Clotet B, Martinez-Picado J, Badia R, Riveira-Muñoz E, Ballana E.

Front Immunol. 2022 Sep 5;13:1001068

Altered T-cell subset distribution in the viral reservoir in HIV-1-infected individuals with extremely low proviral DNA (LoViReTs)

Gálvez C, Urrea V, Garcia-Guerrero MDC, Bernal S, Benet S, Mothe B, Bailón L, Dalmau J, Martinez A, Nieto A, Leal L, García F, Clotet B, Martinez-Picado J, Salgado M.

J Intern Med. 2022 Aug;292(2):308-320

Targeting Macrophage Dysregulation for Viral Infections: Novel Targets for Immunomodulators

Reece MD, Taylor RR, Song C, Gavegnano C.

Front Immunol. 2021 Nov 1;12:768695

VIP-SPOT: an innovative assay to quantify the productive HIV-1 reservoir in the monitoring of cure strategies

Puertas MC, Bayón-Gil Á, Garcia-Guerrero MC, Salgado M, Urrea V, Morón-López S, Peña R, Jiménez-Moyano E, Clotet B, Prado JG, Martinez-Picado J.

mBio. 2021 Jun 29;12(3):e0056021

Extremely low viral reservoir in treated chronically HIV-1-infected individuals

Gálvez C, Urrea V, Dalmau J, Jimenez M, Clotet B, Monceaux V, Huot N, Leal L, González-Soler V, González-Cao M, Müller-Trutwin M, Sáez-Cirión A, García F, Blanco J, Martinez-Picado J, Salgado M.

EBioMedicine. 2020 Jul;57:102830